Journal: Nanoscale Research Letters

Article Title: Strong plasmon-exciton coupling in a hybrid system of gold nanostars and J-aggregates

doi: 10.1186/1556-276X-8-134

Figure Lengend Snippet: Surface-enhanced Raman spectra, scanning electron microscopy image, and Raman micromapping. Surface-enhanced Raman spectrum (red curve) of the hybrid nanostructure of gold nanostars and the J-aggregates of JC1 dye as compared to the Raman spectrum of J-aggregates of JC1 only (black curve). Scanning electron microscopy image and Raman micromapping of tightly bound agglomerates of gold nanostars and J-aggregates of JC1 dye are given in the left and the right insets, respectively.

Article Snippet: The formation of the hybrid structures of two constituent compounds has been further confirmed by surface-enhanced Raman scattering (SERS) measurements using a confocal Raman microscopy setup (Alpha300, 600 mm −1 grating, 3 cm −1 spectral resolution, continuous wave laser excitation at 532 nm, WITec, Ulm, Germany), as the hot spots provided by sharp tips of agglomerated Au nanostars are expected to enhance Raman scattering response of the attached organic compounds [ ].

Techniques: Electron Microscopy

Journal: Journal of Nanobiotechnology

Article Title: Targeted imaging and induction of apoptosis of drug-resistant hepatoma cells by miR-122-loaded graphene-InP nanocompounds

doi: 10.1186/s12951-016-0237-2

Figure Lengend Snippet: A Cellular near-infrared fluorescence and GPMQNs uptake. Inverted fluorescence microscopy of HepG2/ADM cells with 10 mg L −1 GPMQNs, B Control ( Scale bar 50 μm ). B 3D reconstruction of HepG2/ADM cells treated with 10 mg L −1 . GPMQNs of near-infrared fluorescence for intracellular distribution ( Scale bar 50 μm). D Whole body optical imaging examination of HepG2/ADM cells incubated with identical 10 mg L −1 GPMQNs solutions after 24 h incubation; a Control, b 1 mg L −1 red fluorescent modified miR-122, c 10 mg L −1 GPMQNs containing the red fluorescent modified miR-122. E Quantitative assay of GPMQNs on cell membrane permeability based on the LDH release assay; 1 untreated control, 2 resistant HepG2/ADM cells transfected with miR-122 (1 mg L −1 , same concentration as loaded on GPMQN), 3 resistant HepG2/ADM cells incubation with 10 mg L −1 GPMQNs without miR-122, 4 resistant HepG2/ADM cells incubation with 10 mg L −1 GPMQNs (*P < 0.05 compared to the control group)

Article Snippet: HepG2/ADM cells were cultured in 6-well plates, and then were treated with GPMQNs for 1 h. After the washing of the cells, confocal fluorescence microscopy (excitation wavelength at 600 nm) was used to observe the intracellular near-infrared fluorescence (CarlZeiss LSM710, Carl Zeiss, German), and small animal imaging experiments were used to observe the intracellular near-infrared fluorescence.

Techniques: Fluorescence, Microscopy, Control, Optical Imaging, Incubation, Modification, Membrane, Permeability, Lactate Dehydrogenase Assay, Transfection, Concentration Assay